Main problem with my 2000 Lexus rx300 has been the transmission.
I have had my car for 9 years and it is given me some trouble. Especially with the transmission. I had to buy a new one a couple years ago and ever since then the truck has never been the same. It makes a really bad movement when I put it on reverse every single time. Some way worse than others. It also shakes when I am driving it sometimes worse than others. That has been the main problem with this car. And I have had it checked lots of times for these problems but different mechanics keep saying that it is fine and maybe it is just the gas that I am using. Other than that it is been fine.