The fuel filter on the 2000 Ford F-250 is located in the fuel filter housing, which is near the front of the engine after You pop the hood on the driver's side. There's actually a second located on the undercarriage, but the one You'd typically change is the engine one. A compatible replacement for Your truck is the FD-4596, which runs for around $14 on Amazon, and provides the same performance as the OEM part.
Jonathan A.
April 9, 2020
The fuel filter for a 2000 ford f250 should be found on the frame rail, close to mid body.
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